We have just released MonoTouch 6.0.10 which contains support for the new APIs introduced in iOS 6.1, which Apple released just a few hours ago.
From an API perspective, iOS 6.1 was a relatively minor upgrade. There are only a couple of new classes added to MapKit, the MKLocalSearchRequest and MKLocalSearchRequest classes. We have added MapKitSearch to our sample gallery showing how to use the new APIs.
Head out to the Release Notes for MonoTouch 6.0.9 to learn about both the features we introduced in 6.0.9 and the new iOS 6.1 APIs introduced today.